Articles

WHO maternal sepsis statement

World Health Organization. (‎2017)‎. Statement on maternal sepsis. World Health Organization. https://iris.who.int/handle/10665/254608.

Active Prevention and Treatment of Maternal Sepsis (APT-Sepsis)

Lissauer D, Gadama L, Waitt C, Whyte S, Burnside G, Anilkumar A, Makuluni R, Okwaro P, Yang L, Waitt P, Musopole O, Bilesi R, Maseko B, Lwasa J, Mugahi R, Olaro C, Lamorde M, Makuta M, Kachiwaya C, Mkandawire T, Malunga A, Chitsulo N, Abitimo P, Ayabo T, Weeks A, Martin J, Hemming K, Gallos I, Monk EJM, Riches J, Chapuma C, Nanyondo S J, Lorencatto F, Monahan M, Allegranzi B, Dunlop C, Atkins L, Rosala-Hallas A, Roberts T, Gamble C, Malata A, Desmond N, Kommwa E, Merriel A, Parry-Smith W, Smith R, Ndumu I, Williams E, Faque B, Banda G, Nyondo-Mipando AL, Twimukye A, Chater T, Diplas A, Brizuela V, Souza JP, Rylance J, Cheshire J, Hawker L, Coomarasamy A, Bonet M. A Multicomponent Intervention to Improve Maternal Infection Outcomes. N Engl J Med. 2025 Nov 19. doi: 10.1056/NEJMoa2512698.

Global Maternal Sepsis Study publications

Bonet M, Souza JP, Abalos E, Fawole B, Knight M, Kouanda S, Lumbiganon P, Nabhan A, Nadisauskiene R, Brizuela V, Metin Gülmezoglu A. The global maternal sepsis study and awareness campaign (GLOSS): study protocol. Reprod Health. 2018 Jan 30;15(1):16. doi: 10.1186/s12978-017-0437-8.
WHO Global Maternal Sepsis Study (GLOSS) Research Group. Frequency and management of maternal infection in health facilities in 52 countries (GLOSS): a 1-week inception cohort study. Lancet Glob Health. 2020 May;8(5):e661-e671. doi: 10.1016/S2214-109X(20)30109-1.
Brizuela V, Cuesta C, Bartolelli G, Abdosh AA, Abou Malham S, Assarag B, Castro Banegas R, Díaz V, El-Kak F, El Sheikh M, Pérez AM, Souza JP, Bonet M, Abalos E; WHO GLOSS Research Group. Availability of facility resources and services and infection-related maternal outcomes in the WHO Global Maternal Sepsis Study: a cross-sectional study. Lancet Glob Health. 2021 Jul 14:S2214-109X(21)00248-5. doi: 10.1016/S2214-109X(21)00248-5.
Baguiya A, Bonet M, Cecatti JG, Brizuela V, Curteanu A, Minkauskiene M, Jayaratne K, Ribeiro-do-Valle CC, Budianu MA, Souza JP, Kouanda S, on behalf of the WHO Global Maternal Sepsis Study (GLOSS) Research Group. Perinatal outcomes among births to women with infection during pregnancy. Arch Dis Child. 2021 Sep 2:archdischild-2021-321865. doi: 10.1136/archdischild-2021-321865.
Okafor O, Roos N, Abdosh AA, Adesina O, Alaoui Z, Romero WA, Assarag B, Aworinde O, de Bernis L, Castro R, Chrifi H, Day LT, Demissew R, Aceituno MGF, Gadama L, Gashawbeza B, Keke SG, Govule P, Gwako G, Jayaratne K, Komboigo EB, Lara B, Madziyire MG, Mathai M, Moulki R, Moutaouadia I, Munjanja S, Fletes CAO, Ortiz EI, Ouedraogo HG, Qureshi Z, Recidoro ZD, Senanayake H, Soma-Pillay P, Tin KN, Sedami P, Worku D, Bonet M; WHO Global Maternal Sepsis Study- Maternal Death and Near-miss Review Working Group. International virtual confidential reviews of infection-related maternal deaths and near-miss in 11 low- and middle-income countries – case report series and suggested actions. BMC Pregnancy Childbirth. 2022 May 23;22(1):431. doi: 10.1186/s12884-022-04731-x. PMID: 35606709; PMCID: PMC9128080.
Baguiya A, Bonet M, Brizuela V, Cuesta C, Knight M, Lumbiganon P, Abalos E, Kouanda S; WHO Global Maternal Sepsis Study Research Group. Infection-related severe maternal outcomes and case fatality rates in 43 low and middle-income countries across the WHO regions: Results from the Global Maternal Sepsis Study (GLOSS). PLOS Glob Public Health. 2024 Apr 25;4(4):e0003109. doi: 10.1371/journal.pgph.0003109
Ribeiro-do-Valle CC, Bonet M, Brizuela V, Abalos E, Baguiya A, Bellissimo-Rodrigues F, Budianu M, Puscasiu L, Knight M, Lissauer D, Dunlop C, Jacob ST, Shakoor S, Gadama L, Assarag B, Souza JP, Cecatti JG; WHO GLOSS research group. Aetiology and use of antibiotics in pregnancy-related infections: results of the WHO Global Maternal Sepsis Study (GLOSS), 1-week inception cohort. Ann Clin Microbiol Antimicrob. 2024 Feb 24;23(1):21. doi: 10.1186/s12941-024-00681-8
Chimwaza Y, Hunt A, Oliveira-Ciabati L, Bonnett L, Abalos E, Cuesta C, Souza JP, Bonet M, Brizuela V, Lissauer D; World Health Organization Global Maternal Sepsis Study Research Group. Early warning systems for identifying severe maternal outcomes: findings from the WHO global maternal sepsis study. EClinicalMedicine. 2024 Dec 6;79:102981. doi: 10.1016/j.eclinm.2024.102981.

STOP Sepsis campaign publications

Brizuela V, Bonet M, Souza JP, Tunçalp Ö, Viswanath K, Langer A. Factors influencing awareness of healthcare providers on maternal sepsis: a mixed-methods approach. BMC Public Health. 2019 Jun 3;19(1):683. doi: 10.1186/s12889-019-6920-0.
Brizuela V, Bonet M, Trigo Romero CL, Abalos E, Baguiya A, Fawole B, Knight M, Lumbiganon P, Minkauskienė M, Nabhan A, Bique Osman N, Qureshi ZP, Souza JP; World Health Organization Global Maternal Sepsis Study Research Group. Early evaluation of the ‘STOP SEPSIS!’ WHO Global Maternal Sepsis Awareness Campaign implemented for healthcare providers in 46 low, middle and high-income countries. BMJ Open. 2020 May 21;10(5):e036338. doi: 10.1136/bmjopen-2019-036338.

Other publications

D’aloja P, Lega I, Maraschini A, Donati S. WHO GLOSS: uno studio globale per ridurre le morti materne e neonatali da sepsi. Recenti Prog Med 2017;108(9):363-365. doi 10.1701/2745.27987
Compaoré R, Brizuela V, Khisa AM, Gómez AL, Baguiya A, Bonet M, Thorson A, Gitau E, Kouanda S. ‘We always find things to learn from.’ Lessons from the implementation of the global maternal sepsis study on research capacity: a qualitative study. BMC Health Serv Res. 2021 Mar 8;21(1):208. doi: 10.1186/s12913-021-06195-9.
Eddy KE, Zahroh RI, Bohren MA, Bonet M, Homer CSE, Vogel JP. Factors affecting the use of antibiotics and antiseptics to prevent maternal infection at birth: A global mixed-methods systematic review. PLoS One. 2022 Sep 1;17(9):e0272982. doi: 10.1371/journal.pone.0272982. PMID: 36048776; PMCID: PMC9436089
Escobar-Vidarte MF, Fernandez PA, Galindo JS, Valencia-Orozco A, Libreros-Peña L, Peña-Zarate EE, Castro R, Lara BD, Carvajal JA. Factors associated with infection-related severe maternal outcomes in pregnant and recently pregnant women: A secondary analysis of the WHO global maternal sepsis study. Int J Gynaecol Obstet. 2024 Aug 15. doi: 10.1002/ijgo.15857
Dunlop CL, Kilpatrick C, Jones L, Bonet M, Allegranzi B, Brizuela V, Graham W, Thompson A, Cheshire J, Lissauer D. Adapting the WHO hand hygiene ‘reminders in the workplace’ to improve acceptability for healthcare workers in maternity settings worldwide: a mixed methods study. BMJ Open. 2024 Sep 17;14(9):e083132. doi: 10.1136/bmjopen-2023-083132